An important step has been taken for science. Experts from the University of Wisconsin-Madison, United States of AmericaI mentioned that this progress is about to undergo testing in Humans. It was discovered that some cells – made in the laboratory – were photosensitive and that, after separating them, were grouped together.
The research has worked as a culture of these cells outside the human body and may be useful in the future so that dead retinal cells can be replaced in the laboratory.
This step is important in eye transplantation for patients with different visual problems. Because they are part of the same function, the cells form other cells so that they eventually become the retina.
It is basically a tissue located at the back of the eye, whose main responsibility is to interpret signals that come directly from the brain. In this way, vision is created. When the tissue is torn and no longer connected to the brain, the person immediately loses their sight.
The researcher and ophthalmologist on the research, David Jam, stated that this is the final stage of the study and noted that everyone achieved a goal: “We wanted to use the cells of these organelles as replacement parts for the same types of cells that they have been lost in the course of retinal diseases,” the doctor explained.
Research mounts the retina in the laboratory
Cells created in 3D by researchers in the lab in 2014 cause an effect very similar to that of the natural retina that the human body carries. The discovery made in 2022 showed that the same laboratory cell can respond to different stimuli and communicate with others to form connections.
The function of the creation will depend on the connection that the cell will establish within the body itself, consisting of a chemical connection known as a “clamp”, causing an “artificial” junction with the vision cells in the body.
The team’s question was whether these connections were established in reality. In this way they applied the rabies virus to the experiment and saw that retinal cells make connections.
“All of this will eventually lead to human clinical trials, which will be the next step,” Jam noted.
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